In Brazil, reinforced concrete buildings gain more and more space in research and design specifications. This has as its main factor, problems that must be avoided in order to preserve the useful life of buildings, such as the incidence of pathological manifestations. The work aimed at analyzing these manifestations in a public hospital in a serious state of deterioration, problematization, which affects the population of the municipality great concern with the use and occupation of the building. This problem can have its primary incidence in the phases of design, execution or maintenance, which increasingly justifies the relevance of the research. In this way, this work synthesizes parameters of extreme importance in the study of the Pathology of the buildings, leaving in evidence the main problems that these incidents can entail. From this, a case study was carried out at Hospital and Maternidade Santa Rita in the city of Alto Santo / CE, including the execution of tests and the application of the GUT matrix analysis method. The methodology adopted was initially through a survey of bibliographical research to study the problem itself and visual inspection to obtain the diagnosis of the manifestation. The results revealed high indexes of manifestation with causes due to humidity, besides having a great structural problem located in the pillars of the access Hall and some geometric and mapped cracks. After application of the GUT Matrix we saw that the cracks in the concrete structures show high criticality. Thus, it was concluded that hospital safety may be compromised because concrete structures present a critical critical index. We also noticed the various problems caused by humidity in the building, which cause users feelings of repulsion for example. Finally, it is also concluded the need for further studies with tests that prove the true diagnosis of the elements.